Publication date: Oct 18, 2024
Although uveitis after vaccination is rare, reports emerged during the COVID-19 pandemic. We used the pharmacovigilance case/non-case study from 1967 to 2023 to assess the association between vaccines and uveitis. We identified a significant signal for uveitis (reporting OR (ROR), 1. 64; information component (IC), 0. 66) with 1508 reports. This association is pronounced in females of all ages after childhood. Specifically, the COVID-19 messenger RNA vaccines showed the strongest disproportionality signal (ROR, 5. 76; IC, 2. 33), followed by hepatitis B, papillomavirus, Ad (Adenovirus) 5-vectored COVID-19 and influenza vaccines. These findings underscore the importance of surveillance in the postmarketing phase to manage potential adverse events associated with vaccine administration.
| Concepts | Keywords |
|---|---|
| Childhood | Epidemiology |
| Papillomavirus | Uveitis |
| Pharmacovigilance | |
| Postmarketing |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | uveitis |
| disease | MESH | COVID-19 pandemic |
| disease | MESH | hepatitis B |
| pathway | KEGG | Hepatitis B |