Highly selective split intein method for efficient separation and purification of recombinant therapeutic proteins from mammalian cell culture fluid.

Publication date: Nov 08, 2024

Concepts Keywords
Biologics Animals
Decades Bioseparations
Drugs CHO Cells
Efficient Chromatography
Host Chromatography, Affinity
Cricetulus
Downstream processing
Humans
Intein
Inteins
Interferon alpha-2
Interferon alpha-2
Interferon-alpha
Interferon-alpha
Interferon-alpha2b
Protein purification
Recombinant Proteins
Recombinant Proteins
SARS-CoV-2
Self-cleaving affinity tag
Single-Chain Antibodies
Single-Chain Antibodies
Spike Glycoprotein, Coronavirus
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2

Semantics

Type Source Name
disease IDO cell
disease IDO quality
disease IDO protein
drug DRUGBANK Natural alpha interferon
drug DRUGBANK Interferon alfa-n1

Original Article

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