Age and urban-rural disparities in cutaneous melanoma mortality rates in the United States during the COVID-19 pandemic.

Publication date: Nov 01, 2024

Most recent studies on the coronavirus disease 2019 (COVID-19) pandemic and cutaneous melanoma (CM) focused more on delayed diagnosis or advanced presentation. We aimed to ascertain mortality trends of CM between 2012 and 2022, focusing on the effects of the COVID-19 pandemic. In this serial population-based study, the National Vital Statistics System dataset was queried for mortality data. Excess CM-related mortality rates were estimated by calculating the difference between observed and projected mortality rates during the pandemic. Totally there were 108,853 CM-associated deaths in 2012-2022. CM-associated mortality saw a declining trend from 2012 to 2019 overall. However, it increased sharply in 2020 (ASMR 3. 73 per 100,000 persons, 5. 95% excess mortality), and remained high in 2021 and 2022, with the ASMRs of 3. 82 and 3. 81, corresponding to 11. 17% and 13. 20% excess mortality, respectively. The nonmetro areas had the most pronounced rise in mortality with 12. 20% excess death in 2020, 15. 33% in 2021 and 20. 52% in 2022, corresponding to a 4-6 times excess mortality risk compared to large metro areas during the pandemic. The elderly had the most pronounced rise in mortality, but the mortality in the younger population was reduced.

Concepts Keywords
Coronavirus Adolescent
Covid Adult
Reduced Age Factors
Aged
Aged, 80 and over
COVID-19
COVID‐19
cutaneous melanoma
Female
Humans
Male
Melanoma
Melanoma, Cutaneous Malignant
Middle Aged
mortality
Pandemics
Rural Population
SARS-CoV-2
Skin Neoplasms
United States
Urban Population
Young Adult

Semantics

Type Source Name
disease MESH melanoma
pathway KEGG Melanoma
disease MESH COVID-19 pandemic
disease MESH death
disease MESH Melanoma Cutaneous Malignant
disease MESH Skin Neoplasms

Original Article

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