NEW-ONSET PRIMARY ADRENAL INSUFFICIENCY AFTER COVID-19: CASE REPORT.

Publication date: Oct 07, 2024

COVID-19 primarily affects the respiratory system. What comes after the disease is now a greater concern for the scientific world. It is remarkable for causing endocrine organ involvement, particularly in the adrenal glands. However, its effect on the adrenal gland has not been fully elucidated. A case of primary adrenal insufficiency after COVID-19. A 31-year-old female patient who presented with complaints of weakness, anorexia, nausea, recent onset of vomiting, dizziness, and low blood pressure for two months was admitted to the outpatient Department of Endocrinology and Metabolism. After discharge, the patient had routine follow-ups, and here we present the information on the first and seventh month after discharge. The patient was diagnosed with primary adrenal insufficiency with cortisol 1200 pg/mL in the laboratory. In the non-contrast computed tomography taken in the adrenal protocol, the stem and leaves of both adrenal glands are significantly thinned and appear atrophic, the right adrenal gland is hardly distinguished. Hydrocortisone was started. All complaints were resolved within a week, except hyperpigmentation, which was resolved six months later after treatment. Our study support adrenal gland involvement due to COVID-19, further research is needed to obtain data on damage mechanisms.

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Concepts Keywords
Endocrinology COVID-19
Outpatient Primary adrenal insufficiency
Tomography
Vomiting
Week

Semantics

Type Source Name
disease MESH PRIMARY ADRENAL INSUFFICIENCY
disease MESH COVID-19
disease MESH anorexia
disease MESH low blood pressure
pathway REACTOME Metabolism
drug DRUGBANK Hydrocortisone
disease MESH hyperpigmentation
drug DRUGBANK Coenzyme M
disease IDO infectious agent
disease IDO protein
disease MESH autoimmunity
disease MESH infections
drug DRUGBANK Favipiravir
disease IDO infection
disease MESH hypothyroidism
drug DRUGBANK Levothyroxine
disease IDO blood
drug DRUGBANK Potassium
drug DRUGBANK Aldosterone
drug DRUGBANK Sodium Chloride
disease MESH severe acute respiratory syndrome
disease MESH necrosis
disease MESH bleeding
disease MESH inflammation
disease MESH viral infection
disease IDO pathogen
disease IDO host
disease MESH adrenal insufficiency
disease MESH infarction
disease MESH coronavirus infection
disease MESH Infectious Diseases
disease MESH Tuberculosis
pathway KEGG Tuberculosis
disease MESH Respiratory Diseases
drug DRUGBANK L-Valine
disease MESH autoimmune diseases

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