Poxvirus vaccines: the evolution of an 18th-century vaccine to the 21st century.

Publication date: Nov 12, 2024

The unprecedented global spread of monkeypox (mpox) has reinvigorated the pursuit of next-generation poxvirus vaccines. Given the success of the mRNA-lipid nanoparticle (LNP) vaccine platform to vaccinate against SARS-CoV-2, candidate poxvirus mRNA vaccines, as recently reported by Zuiani et al. and Mucker et al. , demonstrate success in nonhuman primate (NHP) models and provide insights into the basis of the protective immune response.

Concepts Keywords
18th immune profiling
Models lipid nanoparticle
Monkeypox mRNA
Nanoparticle nonhuman primate
Vaccines

Semantics

Type Source Name
disease MESH monkeypox
drug DRUGBANK Spinosad
disease IDO immune response

Original Article

(Visited 1 times, 1 visits today)