Publication date: Nov 15, 2024
Limited data exists regarding population immunity against diphtheria, tetanus, and pertussis in Thailand during the post-COVID-19 pandemic period. This study aimed to evaluate the age-specific seroprevalence of anti-diphtheria toxoid (anti-DT) IgG, anti-tetanus toxoid (anti-TT) IgG, and anti-pertussis toxin (anti-PT) IgG in individuals across diverse age groups in Chonburi province, Thailand following the COVID-19 pandemic. Between October 2022 and January 2023, a total of 657 participants from Chonburi Province, Thailand, were included in this study. The participants were categorized into 9 age groups: 70 years. Analysis of anti-DT, anti-TT, and anti-PT IgG levels was conducted using commercial ELISA kits (EUROIMMUN, LcFCbeck, Germany). Overall, 65. 4 % of the population had seroprotection against diphtheria (antibody level ≥0. 1 IU/mL), while 95. 1 % had seroprotection against tetanus (antibody level ≥0. 1 IU/mL). The 31-40 years age group exhibited the lowest seroprotection for diphtheria (48. 9 %), and the >70 years age group had the lowest seroprotection for tetanus (73. 3 %). The
Concepts | Keywords |
---|---|
Antibodies | Diphtheria |
Germany | Pertussis |
Pandemic | Population |
Thailand | Seroprevalence |
Tetanus |
Semantics
Type | Source | Name |
---|---|---|
disease | MESH | diphtheria |
disease | MESH | tetanus |
disease | MESH | pertussis |
pathway | KEGG | Pertussis |
disease | MESH | COVID-19 pandemic |
drug | DRUGBANK | Clostridium tetani toxoid antigen (formaldehyde inactivated) |