Seroprevalence of antibodies against diphtheria, tetanus, and pertussis across various age groups during the post-COVID-19 pandemic period in Chonburi Province, Thailand.

Publication date: Nov 15, 2024

Limited data exists regarding population immunity against diphtheria, tetanus, and pertussis in Thailand during the post-COVID-19 pandemic period. This study aimed to evaluate the age-specific seroprevalence of anti-diphtheria toxoid (anti-DT) IgG, anti-tetanus toxoid (anti-TT) IgG, and anti-pertussis toxin (anti-PT) IgG in individuals across diverse age groups in Chonburi province, Thailand following the COVID-19 pandemic. Between October 2022 and January 2023, a total of 657 participants from Chonburi Province, Thailand, were included in this study. The participants were categorized into 9 age groups: 70 years. Analysis of anti-DT, anti-TT, and anti-PT IgG levels was conducted using commercial ELISA kits (EUROIMMUN, LcFCbeck, Germany). Overall, 65. 4 % of the population had seroprotection against diphtheria (antibody level ≥0. 1 IU/mL), while 95. 1 % had seroprotection against tetanus (antibody level ≥0. 1 IU/mL). The 31-40 years age group exhibited the lowest seroprotection for diphtheria (48. 9 %), and the >70 years age group had the lowest seroprotection for tetanus (73. 3 %). The

Concepts Keywords
Antibodies Diphtheria
Germany Pertussis
Pandemic Population
Thailand Seroprevalence
Tetanus

Semantics

Type Source Name
disease MESH diphtheria
disease MESH tetanus
disease MESH pertussis
pathway KEGG Pertussis
disease MESH COVID-19 pandemic
drug DRUGBANK Clostridium tetani toxoid antigen (formaldehyde inactivated)

Original Article

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