SmartGraph API: Programmatic Knowledge Mining in Network-Pharmacology Setting.

Publication date: Dec 04, 2024

The recent SmartGraph platform facilitates the execution of complex drug-discovery workflows with ease in the network-pharmacology paradigm. However, at the time of its publication we identified the need for the development of an Application Programming Interface (API) that could promote biomedical data integration and hypothesis generation in an automated manner. This need was magnified at the time of the COVID-19 pandemic. This study addresses the absence of such an API. Accordingly, most functionalities of the original platform were implemented within the SmartGraph API. We demonstrate that by using the API it is possible to transform the original semiautomated workflow behind the Neo4COVID19 database to a fully automated one. The availability of the SmartGraph API lends a significant improvement to the programmatic integration of network-pharmacology-oriented knowledge graphs and analytics, as well as predictive functionalities and workflows.

Concepts Keywords
Biomedical Api
Informatics Automated
Mining Execution
Neo4covid19 Facilitates
Pandemic Functionalities
Integration
Mining
Network
Original
Pharmacology
Programmatic
Recent
Setting
Smartgraph
Workflows

Semantics

Type Source Name
drug DRUGBANK Alpha-1-proteinase inhibitor
disease MESH COVID-19 pandemic

Original Article

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