A Case of Triple Respiratory Coinfection: COVID-19, Enterovirus, and Parainfluenza.

Publication date: Nov 01, 2024

We report a case of a 34-year-old female who presented to the emergency department with fever, nausea, vomiting, and diarrhea following a suspected foodborne illness. She tested positive for COVID-19, human parainfluenza virus type 4, and enterovirus/rhinovirus in the hospital. She subsequently developed hypoxia, hypotension, and sepsis. Blood work revealed leukocytosis and elevated inflammatory markers. Imaging of her abdomen showed fluid-filled bowel loops suggesting acute gastroenteritis and colitis of infectious or inflammatory etiology. She was initially treated with antibiotics for a suspected bacterial infection. However, her cultures resulted negative and her symptoms slowly improved with supportive care including probiotics and a low-fat diet. Due to her persistent shortness of breath related to her COVID-19 infection, she was started on a course of oral prednisone due to the anti-inflammatory effects of steroids. She was discharged home in stable condition with close outpatient follow-up. This study highlights the clinical challenges of managing multiple viral infections, particularly with concurrent COVID-19.

Concepts Keywords
Bacterial coinfection
Foodborne covid-19
Gastroenteritis enterovirus
Outpatient parainfluenza
Rhinovirus superinfection

Semantics

Type Source Name
disease MESH Coinfection
disease MESH COVID-19
disease MESH Parainfluenza
disease MESH emergency
disease MESH hypoxia
disease MESH hypotension
disease MESH sepsis
disease IDO blood
disease MESH leukocytosis
disease MESH gastroenteritis
disease MESH colitis
disease MESH etiology
disease MESH bacterial infection
disease MESH shortness of breath
disease MESH infection
drug DRUGBANK Prednisone
disease MESH viral infections
disease MESH superinfection

Original Article

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