Publication date: Jan 06, 2025
Two complementary works by Chan et al. (https://doi. org/10. 1084/jem. 20231725), and Ru et al. (https://doi. org/10. 1084/jem. 20240010), identify defective RNA processing as the root cause of impaired antiviral immunity against SARS-CoV2 in the human brainstem. These studies provide molecular insight into virus-associated severe brainstem encephalitis through PKR inactivation.
Concepts | Keywords |
---|---|
Antiviral | Animals |
Chan | Brain Stem |
Encephalitis | COVID-19 |
Rna | eIF-2 Kinase |
eIF-2 Kinase | |
Humans | |
RNA, Viral | |
RNA, Viral | |
SARS-CoV-2 |
Semantics
Type | Source | Name |
---|---|---|
disease | MESH | encephalitis |
disease | MESH | COVID-19 |
Original Article
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