Publication date: Dec 04, 2024
Acute tubular injury is one of the main causes of acute tubular injury (acute kidney injury ) in patients with COVID-19 infection. Autoimmune hemolytic anemia (AIHA) is also one of the autoimmune complications of COVID-19. However, AIHA accompanied by acute tubulointerstitial nephritis (ATIN) caused by SARS-CoV-2 is rarely reported. Here, we report a kidney transplant recipient who underwent graftectomy owing to ATIN accompanied by AIHA, possibly exacerbated by COVID-19 infection. A 32-year-old male renal allograft recipient owing to immunoglobulin A nephropathy visited the emergency department owing to dyspnea and general weakness. Three weeks earlier, the patient had been transplanted with deceased-donor kidney with full HLA-A, -B, -DR match, and had been on tacrolimus, prednisolone, and mycophenolate since then. At the time of the visit, laboratory findings revealed hemoglobin of 2. 4 g/dL, reticulocyte of 21. 7%, total bilirubin of 1. 9 mg/dL, direct bilirubin of 0. 3 mg/dL, lactate dehydrogenase of 946 U/L, haptoglobin of
| Concepts | Keywords |
|---|---|
| Dehydrogenase | Accompanied |
| Dyspnea | Acute |
| Immunoglobulin | Aiha |
| Kidney | Anemia |
| Weeks | Autoimmune |
| Covid | |
| Dl | |
| Hemolytic | |
| Infection | |
| Injury | |
| Kidney | |
| Owing | |
| Recipient | |
| Transplant | |
| Tubulointerstitial |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Autoimmune Hemolytic Anemia |
| disease | MESH | COVID-19 |
| disease | MESH | Infection |
| disease | MESH | Acute Tubulointerstitial Nephritis |
| disease | MESH | causes |
| disease | MESH | acute kidney injury |
| disease | MESH | complications |
| disease | MESH | immunoglobulin A nephropathy |
| disease | MESH | emergency |
| disease | MESH | dyspnea |
| drug | DRUGBANK | Tacrolimus |
| drug | DRUGBANK | Prednisolone |
| drug | DRUGBANK | Mycophenolic acid |