Publication date: Jan 01, 2025

This study evaluates the prognostic significance of pleural effusion (PE) in COVID-19 patients across thirteen centers in Germany, aiming to clarify its role in predicting clinical outcomes. In this retrospective analysis within the RACOON project (Radiological Cooperative Network of the COVID-19 pandemic), 1183 patients (29. 3 % women, 70. 7 % men) underwent chest CT to assess PE. We investigated PE’s association with 30-day mortality, ICU admission, and the need for mechanical ventilation. PE was detected in 31. 5 % of patients, showing a significant correlation with 30-day mortality (47. 5 % in non-survivors vs. 27. 3 % in survivors, p

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