A Complex Case of COVID-19 Pneumonitis in a Patient With Follicular Lymphoma.

A Complex Case of COVID-19 Pneumonitis in a Patient With Follicular Lymphoma.

Publication date: Nov 01, 2024

Protracted COVID-19 is increasingly recognised in immunocompromised patients, particularly those with haematological malignancies. Here, we present the case of a patient with protracted COVID-19 and an underlying B-cell malignancy. Standard COVID-19 treatment with remdesivir and steroids proved ineffective in this patient as she continued to have evolving ground-glass opacities on imaging. A multidisciplinary involvement altered treatment to include a combination of antivirals nirmatrelvir/ritonavir (Paxlovid) and remdesivir, a monoclonal antibody and immunoglobulins leading to a clinical cure. This report highlights the need for a more tailored approach in this patient sub-group than the rest of the population.

Concepts Keywords
Covid covid-19
Haematological cycle threshold
Immunocompromised ground-glass opacity
Ineffective hematologic malignancy
immunocompromised

Semantics

Type Source Name
disease MESH COVID-19
disease MESH Pneumonitis
disease MESH Follicular Lymphoma
disease MESH immunocompromised patients
disease MESH malignancies
disease IDO cell
drug DRUGBANK Ritonavir
disease MESH hematologic malignancy

Original Article

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