In COVID-19 Patients Supported with Extracorporeal Membrane Oxygenation, Intensive Care Unit Mortality Is Associated with the Blood Transfusion Rate.

In COVID-19 Patients Supported with Extracorporeal Membrane Oxygenation, Intensive Care Unit Mortality Is Associated with the Blood Transfusion Rate.

Publication date: Dec 04, 2024

Background: The COVID-19 pandemic markedly increased the number of patients with infection-related acute respiratory distress syndrome who required extracorporeal membrane oxygenation (ECMO) and multiple blood transfusions. This study aimed to assess a potential correlation between the daily rate of transfused blood products and the intensive care unit (ICU) outcome of ECMO-supported COVID-19 patients. Methods: Data were retrieved from the electronic databases of three Israeli tertiary care centers. All COVID-19 patients treated with ECMO for >3 days in these centers between July 2020 and November 2021 were included in the analysis. Results: The study incorporated 106 patients [median age 49 (17-73) years]. The median numbers of ECMO days and daily transfused packed red blood cell (PRBC) units were 20. 5 (4-240) and 0. 61 (0-2. 82), respectively. In multivariate analysis, age ≥50 years was an independent factor for ICU mortality [odds ratio (OR) 4. 47). In ECMO-supported patients for

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Concepts Keywords
Daily COVID-19
July extracorporeal membrane oxygenation
November
Pandemic
Transfusion

Semantics

Type Source Name
disease MESH COVID-19
disease IDO blood
disease MESH infection
disease MESH acute respiratory distress syndrome
disease IDO cell
drug DRUGBANK Coenzyme M

Original Article

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