Factors influencing the time to COVID-19 antigen tests negative conversion among students at a Chinese university: a retrospective analysis.

Factors influencing the time to COVID-19 antigen tests negative conversion among students at a Chinese university: a retrospective analysis.

Publication date: Dec 18, 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause repeated infections. China experienced an outbreak of COVID-19 (coronavirus disease 2019) after the Chinese government changed its COVID-19 policy in December 2022. However, little is known about the influencing factors, such as a history of previous infection and vaccine dose, and whether these factors affect the time at which the antigen test results become negative for SARS-CoV-2. Boarding colleges and universities are prone to outbreaks caused by COVID-19. Therefore, we investigated the factors influencing the time of COVID-19 antigen tests conversion at one university from April to June 2023. This study included college students from one university in Guangzhou who tested positive for the COVID-19 antigen and collected information such as sex, history of previous COVID-19 infection, vaccination dose, symptom onset date, and antigen tests conversion date for retrospective analysis. Chi-square tests or t-tests were used to compare differences between groups. A total of 255 college students were included in this study. In addition to fever, the most common symptoms were sore throat, nasal symptoms and fatigue. The average time to antigen tests negative conversion of patients with their first infection was 6. 12 +/- 1. 83 days, and that of patients with their second infection was 4. 70 +/- 1. 43 days. The difference between the groups was statistically significant (P 

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Concepts Keywords
43days Adolescent
China Adult
Coronavirus Antigens, Viral
Students Antigens, Viral
China
COVID-19
COVID-19
COVID-19 Serological Testing
Female
Humans
Male
Retrospective Studies
Retrospective study
SARS-CoV-2
Students
Symptom
Time Factors
Universities
University student
Young Adult

Semantics

Type Source Name
disease MESH COVID-19
disease MESH infections
disease IDO history
disease IDO infection
disease IDO symptom
disease MESH sore throat
disease MESH Long Covid
disease MESH Infectious Diseases
pathway REACTOME Reproduction
drug DRUGBANK Coenzyme M
disease MESH reinfections
disease IDO nucleic acid
disease IDO country
drug DRUGBANK Tretamine
drug DRUGBANK Etoperidone
drug DRUGBANK Gold
disease MESH secondary infection
disease MESH hyposmia
disease MESH emergency
drug DRUGBANK Polyethylene glycol
disease MESH conjunctivitis
disease MESH breakthrough infection
disease MESH viral load
disease IDO immune response
drug DRUGBANK (S)-Des-Me-Ampa
disease MESH viral shedding
disease MESH Influenza
drug DRUGBANK Guanosine

Original Article

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