Publication date: Dec 19, 2024
To determine if pre-operative infection with COVID-19 increased risk for post-operative venous thromboembolism (VTE) in patients undergoing arthroscopic knee surgery. . PearlDiver Mariner 165 database was queried for patients undergoing knee arthroscopy between 2010 through October, 2022. Patients were categorized by history of COVID-19 diagnosis and timing in relation to surgery. Multivariate logistic regression was performed to isolate the effect of COVID-19 diagnosis on post-operative VTE rates. Covariates included age, obesity, smoking, oral contraceptive pill use, hypertension, coronary artery disease, congestive heart failure, malignancy, renal disease and diabetes. A total of 954,294 patients met inclusion criteria and 7,637 patients experienced VTE, including deep vein thrombosis (n = 5,830, 0. 61%) and pulmonary embolism (n=2,790, 0. 29%). Patients with a COVID-19 diagnosis prior to surgery (7,858) had an overall higher incidence of VTE (1. 72%) compared to patients without a pre-operative COVID-19 diagnosis (0. 81%) (p < 0. 001). There was no difference in VTE incidence amongst patients with a pre-operative COVID-19 diagnosis undergoing knee arthroscopy in the pre- and post-COVID-vaccination eras (OR 0. 82, 95% CI = 0. 51 - 1. 31, p=0. 48). Multivariate regression accounting for covariates showed that patients with a pre-operative COVID-19 diagnosis within 6 weeks before arthroscopy had significantly increased odds of experiencing post-operative VTE (OR 1. 68, 95% CI 1. 09-2. 45, p=0. 012). There was no significant difference in VTE risk between patients with a pre-operative COVID-19 diagnosis between 6-12 weeks before arthroscopy and more than 12 weeks before arthroscopy compared to those with no prior COVID-19 diagnosis. COVID-19 diagnosis within 6 weeks preceding arthroscopic knee surgery leads to a significantly higher risk for postoperative VTE. III, retrospective case control study.
Concepts | Keywords |
---|---|
Diabetes | Arthroscopic |
October | Arthroscopy |
Pearldiver | Covid |
Surgery | Diagnosis |
Weeks | Higher |
Knee | |
Leads | |
Operative | |
Post | |
Pre | |
Risk | |
Surgery | |
Undergoing | |
Vte | |
Weeks |
Semantics
Type | Source | Name |
---|---|---|
disease | MESH | COVID-19 |
disease | MESH | Venous Thromboembolism |
disease | MESH | infection |
disease | IDO | history |
disease | MESH | obesity |
disease | MESH | hypertension |
disease | MESH | coronary artery disease |
disease | MESH | congestive heart failure |
disease | MESH | malignancy |
drug | DRUGBANK | Methionine |
disease | MESH | deep vein thrombosis |
disease | MESH | pulmonary embolism |