Telemedicine-based exercise intervention in cancer survivors: a non-randomized controlled trial.

Telemedicine-based exercise intervention in cancer survivors: a non-randomized controlled trial.

Publication date: Dec 23, 2024

Cancer survivors (CS) often experience treatment-related side effects, such as fatigue, and have reduced physical function. Regular physical activity has been demonstrated to reduce these symptoms and improve cardiopulmonary fitness. Digital solutions are needed to optimize exercise options for CS in aftercare, especially given the significant limitations during the Covid-19 pandemic. This two-armed, non-randomized, controlled intervention study for CS aims to investigate whether a telemedicine-based exercise intervention is as effective as the current standard of care for oncological exercise therapy in aftercare. Patients in the intervention group (nā€‰=ā€‰61) performed a telemedicine-based exercise program (TE) and patients in the control group (nā€‰=ā€‰31) participated in an existing rehabilitation sports group (RG) over a six-month intervention period. The primary outcome was cardiopulmonary fitness measured by VOpeak; secondary outcomes included quality of life (QoL), fatigue, and physical activity. A non-inferiority analysis was performed with a predefined non-inferiority margin for relative VOpeak of -1. 50 ml/min/kg. Although TE demonstrated a slight advantage in relative VOpeak compared to RG (adjusted mean difference of 0. 55 ml/min/kg [95% CI: -2. 74; 3. 84]), the non-inferiority was not statistically significant. Nevertheless, the implementation of a telemedicine-based exercise intervention indicates that individual patients respond well to this type of exercise program and benefit from the intervention, particularly in terms of QoL. Finding an individualized program for each cancer survivor is the overarching goal. A telemedicine-based exercise intervention may be a promising option, particularly for younger patients.

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Concepts Keywords
50ml Adult
Cardiopulmonary Aged
Pandemic Cancer Survivors
Predefined Cancer survivors
Therapy Cardiorespiratory Fitness
Controlled study
COVID-19
COVID-19
Exercise
Exercise oncology
Exercise Therapy
Fatigue
Female
Humans
Male
Middle Aged
Neoplasms
Quality of Life
SARS-CoV-2
Supportive cancer care
Telemedicine
Wearable activity tracker

Semantics

Type Source Name
disease IDO intervention
disease MESH cancer
disease MESH Covid-19 pandemic
disease IDO quality
drug DRUGBANK Coenzyme M
disease MESH coronary heart disease
disease MESH respiratory diseases
disease MESH lifestyle
drug DRUGBANK Methionine
disease MESH hypertrophy
drug DRUGBANK BIA
disease IDO blood
drug DRUGBANK Oxygen
disease IDO symptom
disease MESH clinical relevance
disease MESH infection
disease MESH lymphoma
disease MESH Leukemia
disease MESH Metastasis
disease MESH Relapse
disease MESH Marital status
drug DRUGBANK Ethanol
drug DRUGBANK Tropicamide
disease IDO role
drug DRUGBANK Pentaerythritol tetranitrate
disease IDO site
disease MESH prostate cancer
pathway KEGG Prostate cancer
disease MESH peripheral neuropathy
drug DRUGBANK Isoxaflutole
disease MESH breast cancer related lymphedema
disease MESH cardiovascular disease
disease MESH ovarian Cancer
disease MESH sedentary behavior
disease MESH anemia
disease IDO country
pathway REACTOME Reproduction

Original Article

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