Determination of Oxidative Stress and Copeptin Levels of COVID-19 According to the Clinical Course.

Determination of Oxidative Stress and Copeptin Levels of COVID-19 According to the Clinical Course.

Publication date: Dec 28, 2024

COVID-19, caused by the novel coronavirus SARS-CoV-2, is characterized by hyperinflammation, which can trigger oxidative stress. At the same time, COVID-19 is accompanied by both psychological and physical stress. Copeptin, a novel stress marker, has been shown to predict disease outcomes in stress-induced diseases. In this study, we aimed to explore the potential of copeptin, with inflammatory and oxidative stress markers, in distinguishing between different clinical courses of COVID-19. This case-control study included 75 participants: 25 COVID-19 patients hospitalized in the intensive care unit (ICU), 25 non-ICU COVID-19 patients, and 25 healthy individuals. 64% of the ICU patients received corticosteroid treatment for 4-10 days before sampling. Serum concentrations of the study parameters were assessed by enzyme-linked immunosorbent assay (ELISA) and compared between the study groups. Serum IL-6 levels (p

Concepts Keywords
Coronavirus Copeptin
Elisa Corticosteroids
Healthy COVID-19
Immunosorbent Inflammation
Psychological Oxidative stress

Semantics

Type Source Name
disease MESH Oxidative Stress
disease MESH COVID-19
disease MESH Clinical Course
disease IDO assay
disease MESH Inflammation

Original Article

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