Patterns of kidney diseases diagnosed by kidney biopsy and the impact of the COVID-19 pandemic in Yogyakarta, Indonesia: A single-center study.

Patterns of kidney diseases diagnosed by kidney biopsy and the impact of the COVID-19 pandemic in Yogyakarta, Indonesia: A single-center study.

Publication date: Dec 25, 2024

Glomerular diseases rank third among the causes of chronic kidney disease worldwide and in Indonesia, and its burden continues to increase, especially regarding the sociodemographic index. Kidney biopsy remains the gold standard for the diagnosis and classification of glomerular diseases. It is crucial for developing treatment plans, determining the degree of histologic changes, and identifying disease relapse. To describe the patterns of biopsy-proven kidney diseases in adult patients. We retrospectively reviewed the demographic, histopathologic, clinical, and laboratory data of 75 adult patients with biopsy-proven kidney diseases at our institution recorded from 2017 to 2022. Among the patients, 43 (57. 3%) were females, and the mean age was 31. 52 years +/- 11. 70 years. The most common histopathologies were lupus nephritis (LN) (33. 3%), minimal change disease (MCD) (26. 7%), and focal segmental glomerulosclerosis (10. 7%). LN (41. 7%) was frequently diagnosed in women and MCD (28. 1%) in men. The most common cause of nephritic syndrome was LN (36. 7%) and of nephrotic syndrome was MCD (40%). Different kidney disease patterns were observed in different sexes, age categories, clinical syndromes, and biopsy dates relative to the coronavirus disease 2019 pandemic.

Concepts Keywords
Coronavirus Epidemiology
Females Glomerular diseases
Indonesia Kidney biopsy
Kidney Kidney diseases
Renal biopsy

Semantics

Type Source Name
disease MESH kidney diseases
disease MESH COVID-19 pandemic
disease MESH causes
disease MESH chronic kidney disease
drug DRUGBANK Gold
disease MESH relapse
disease MESH lupus nephritis
disease MESH minimal change disease
disease MESH MCD
disease MESH focal segmental glomerulosclerosis
disease MESH syndrome
disease MESH nephrotic syndrome

Original Article

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