Publication date: Dec 28, 2024
Invasive fungal infections have been reported as complications with significant mortality and morbidity in patients hospitalized with COVID-19. This study aimed to evaluate the clinical characteristics and outcomes of candidaemia patients with COVID-19 and to investigate the association between COVID-19 and mortality in candidaemia patients. This retrospective study included candidaemia patients aged 18 years or older admitted to four university-affiliated tertiary hospitals in South Korea between January 1, 2020, and December 31, 2022. The COVID-19 group comprised patients diagnosed with COVID-19 before the onset of candidaemia. Clinical features and outcomes were compared between the COVID-19 and non-COVID-19 groups. Multivariate logistic regression analyses were performed to identify risk factors related to 30-day mortality. Of the 355 patients diagnosed with candidaemia, 39 (11. 0%) had a prior diagnosis of COVID-19. The COVID-19 group exhibited greater rates of systemic corticosteroid use (20. 5% vs. 8. 9%, p = 0. 042), central venous catheter use (74. 4% vs. 57. 3%, p = 0. 041), and mechanical ventilation (53. 8% vs. 31. 6%, p = 0. 006) before the onset of candidaemia. The COVID-19 group had a greater rate of septic shock at the onset of candidaemia (61. 5% vs. 32. 0%, p
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Concepts | Keywords |
---|---|
Catheter | Candidaemia |
December | COVID-19 |
Fungal | Mechanical ventilation |
Korea | Mortality |
University |