Invasive group A streptococcal infections as a consequence of coexisting or previous viral infection in the post-COVID-19 pandemic period.

Invasive group A streptococcal infections as a consequence of coexisting or previous viral infection in the post-COVID-19 pandemic period.

Publication date: Jan 01, 2025

Group A Streptococci (GAS) may cause infections of the pharynx and soft tissues and invasive infections in children (iGAS). A significant increase in severe iGAS infections has been reported in Europe since the fall of 2022. This retrospective study aims to analyse clinical data of children with invasive and non-invasive GAS infections in the post-COVID-19 pandemic era, searching for predisposing factors to developing invasive infections. History and clinical data of patients hospitalised due to or with coexisting GAS infections were analysed. iGAS and non-iGAS infections were compared. The cohort comprised 45 children (median age 7 years). 31(69 %) children developed iGAS infections – sepsis with toxic shock syndrome (TSS) (4 children-13 %), deep soft tissue infections (3-10 %), meningitis (2-6 %), pneumonia (2-6 %) or respiratory tract infections – sinusitis or otitis (4-12 %). iGAS children developed complications more frequently (100 % vs 21 %, p  14. 94 mg/dl were significant risk factors.

Concepts Keywords
Pandemic Adolescent
Streptococci Child
Viral Child, Preschool
Children
Coinfection
COVID-19
Female
GAS
Humans
Infant
Invasive infections
Male
Outbreak
Retrospective Studies
Risk Factors
SARS-CoV-2
Shock, Septic
Soft Tissue Infections
Streptococcal Infections
Streptococcus pyogenes
Streptococcus pyogenes
Virus Diseases

Semantics

Type Source Name
disease MESH group A streptococcal infections
disease MESH viral infection
disease MESH COVID-19 pandemic
disease MESH infections
disease IDO history
disease MESH sepsis
disease MESH toxic shock syndrome
disease MESH soft tissue infections
disease MESH meningitis
disease MESH pneumonia
disease MESH respiratory tract infections
disease MESH sinusitis
disease MESH otitis
disease MESH complications
disease MESH Coinfection

Original Article

(Visited 1 times, 1 visits today)