A data-driven approach to study temporal characteristics of COVID-19 infection and death Time Series for twelve countries across six continents.

A data-driven approach to study temporal characteristics of COVID-19 infection and death Time Series for twelve countries across six continents.

Publication date: Jan 03, 2025

In this work, we implement a data-driven approach using an aggregation of several analytical methods to study the characteristics of COVID-19 daily infection and death time series and identify correlations and characteristic trends that can be corroborated to the time evolution of this disease. The datasets cover twelve distinct countries across six continents, from January 22, 2020 till March 1, 2022. This time span is partitioned into three windows: (1) pre-vaccine, (2) post-vaccine and pre-omicron (BA. 1 variant), and (3) post-vaccine including post-omicron variant. This study enables deriving insights into intriguing questions related to the science of system dynamics pertaining to COVID-19 evolution. We implement a set of several distinct analytical methods for: (a) statistical studies to estimate the skewness and kurtosis of the data distributions; (b) analyzing the stationarity properties of these time series using the Augmented Dickey-Fuller (ADF) tests; (c) examining co-integration properties for the non-stationary time series using the Phillips-Ouliaris (PO) tests; (d) calculating the Hurst exponent using the rescaled-range (R/S) analysis, along with the Detrended Fluctuation Analysis (DFA), for self-affinity studies of the evolving dynamical datasets. We notably observe a significant asymmetry of distributions shows from skewness and the presence of heavy tails is noted from kurtosis. The daily infection and death data are, by and large, nonstationary, while their corresponding log return values render stationarity. The self-affinity studies through the Hurst exponents and DFA exhibit intriguing local changes over time. These changes can be attributed to the underlying dynamics of state transitions, especially from a random state to either mean-reversion or long-range memory/persistence states. We conduct systematic studies covering a widely diverse time series datasets of the daily infections and deaths during the evolution of the COVID-19 pandemic. We demonstrate the merit of a multiple analytics frameworks through systematically laying down a methodological structure for analyses and quantitatively examining the evolution of the daily COVID-19 infection and death cases. This methodology builds a capability for tracking dynamically evolving states pertaining to critical problems.

Open Access PDF

Concepts Keywords
Continents Co-integration
Covid COVID-19 time series
Daily Detrended Fluctuation Analysis
Death Heavy-Tailed distribution
Vaccine Hurst exponents
Self-Affinity studies
State transitions
Stationarity

Semantics

Type Source Name
disease MESH COVID-19
disease MESH infection
disease MESH death
pathway REACTOME Reproduction
pathway KEGG Coronavirus disease
drug DRUGBANK Indoleacetic acid
disease IDO country
disease IDO process
drug DRUGBANK Ranitidine
disease MESH tic
drug DRUGBANK Coenzyme M
drug DRUGBANK Esomeprazole
drug DRUGBANK L-Valine
disease MESH Severe Acute Respiratory Syndrome
drug DRUGBANK Etoperidone
disease MESH uncertainty
drug DRUGBANK (S)-Des-Me-Ampa
drug DRUGBANK Thiocolchicoside
disease IDO virulence
drug DRUGBANK Methyl isocyanate
drug DRUGBANK D-Alanine
disease IDO intervention
drug DRUGBANK Huperzine B
disease MESH Infectious Diseases
disease IDO algorithm
drug DRUGBANK Ademetionine
disease MESH causality

Original Article

(Visited 1 times, 1 visits today)