Mpox Recrudescence after SARS-CoV-2 Coinfection in a Patient with AIDS.

Mpox Recrudescence after SARS-CoV-2 Coinfection in a Patient with AIDS.

Publication date: Dec 31, 2024

People living with HIV (PLWH) are known to exhibit more severe or prolonged symptoms of mpox (formerly monkeypox). However, the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on PLWH with mpox has not been adequately described. We report a case of mpox in an AIDS patient who had recurrent symptoms due to SARS-CoV-2 infection. The patient presented with a low CD4+ lymphocyte count (CD4 count) without antiretroviral therapy (ART) and suffered from severe mpox. The ART was initiated 17 days after the diagnosis of mpox, and the patient’s skin lesions began crusting after 1 week of ART. However, after a SARS-CoV-2 infection, the mpox flared up again. The patient presented with more severe symptoms than those during the initial bout and with rectal involvement. We speculate that SARS-CoV-2 infection might cause a recrudescence of mpox in AIDS patients, which requires further investigation.

Concepts Keywords
Hiv Aids
Monkeypox Art
Severe Cd4
Therapy Count
Week Cov
Infection
Mpox
Patient
Plwh
Presented
Recrudescence
Sars
Severe
Symptoms
Therapy

Semantics

Type Source Name
disease MESH Recrudescence
disease MESH Coinfection
disease MESH AIDS
disease MESH monkeypox
disease MESH SARS-CoV-2 infection
pathway REACTOME SARS-CoV-2 Infection

Original Article

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