Publication date: Jan 21, 2025
Objectives: To assess the changes in epidemiologic and clinical characteristics of respiratory syncytial virus (RSV) infection among inpatient under 3 months of age with lower respiratory tract infection (LRTI) in different stages of the SARS-CoV-2 pandemic. Methods: A retrospective cohort study was conducted. Clinical data on general condition and laboratory tests were collected from 3 144 RSV-positive LRTI infants less than 3 months of age hospitalized at Children’s Hospital, Zhejiang University School of Medicine from January 2017 to January 2024. Based on the admission date, all patients were categorized into three groups: pre-SARS-CoV-2 infection, during SARS-CoV-2 infection and after SARS-CoV-2 infection. Clinical data from three groups of patients were compared using ANOVA or chi-square test or Kruskal Wallis text to assess the impact of the SARS-CoV-2 infection on the epidemiological and clinical characteristics of RSV. Results: Among the 3 144 RSV-positive children, there were 1 872 males and 1 272 females, with an age of 42 (24, 61) d. The pre-SARS-CoV-2 infection, during SARS-CoV-2 infection and after SARS-CoV-2 infection in 1 224, 1 173 and 747 cases respectively. There were statistically significant differences in RSV infection in winter, summer and autumn (all P
| Concepts | Keywords |
|---|---|
| Females | Assess |
| Inpatient | Characteristics |
| Summer | Clinical |
| Virus | Cov |
| Winter | Infants |
| Infection | |
| Lrti | |
| Months | |
| Pandemic | |
| Positive | |
| Respiratory | |
| Rsv | |
| Sars | |
| Syncytial | |
| Virus |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | respiratory syncytial virus infection |
| disease | MESH | infection |
| disease | MESH | SARS-CoV-2 infection |
| pathway | REACTOME | SARS-CoV-2 Infection |