Health Resort Treatment Mitigates Neuropsychiatric Symptoms in Long COVID Patients: A Retrospective Study.

Publication date: Jan 19, 2025

Among the neuropsychiatric symptoms of long COVID, the following may be listed: sleep disturbances, headaches, anxiety, depression, dizziness, numbness, memory loss, and concentration difficulties. Various therapies have been implemented to mitigate these symptoms; however, health resort treatments that utilize a wide range of modalities stimulating multidirectional biological reactions may also be effective. The aim of this study was to assess the severity of neuropsychiatric symptoms in long COVID patients who qualified for health resort treatment, evaluate the effectiveness of health resort treatment in this group of patients, and evaluate the effect of balneological factors in the treatment course. A retrospective analysis of the medical records of 120 people with long COVID (69 women and 51 men) aged 42-79 who underwent health resort treatment in 2021 was performed. People were eligible for treatment at a lowland health resort based on a valid referral from a doctor. The treatment included balneological therapies, physical medicine modalities, exercise programs, health education, and psychological support. Patients assessed the severity of persistent neuropsychiatric symptoms on a 0-10 point scale before and after treatment. After the treatment, the greatest improvement was noted in sleep disorders (2. 47 +/- 2. 23 points vs. 0. 86 +/- 1. 25 points, p < 0. 00001) and dizziness (1. 39 +/- 1. 94 points vs. 0. 34 +/- 0. 76 points, p < 0. 00001). The lowest improvement was observed in memory disorders (2. 68 +/- 2. 5 points vs. 1 +/- 1. 4 points, p < 0. 00001). Patients with long COVID who qualified for health resort treatment reported mild neuropsychiatric symptoms. Health resort treatment mitigates neuropsychiatric symptoms, as it is a complex approach. Treatment that includes balneological factors improves symptoms to a greater extent. This method of treatment should be integrated into the standard treatment for long COVID.

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Concepts Keywords
Basel health resort treatment
Neuropsychiatric long COVID
Resort neurological disorders
Sleep persistent symptoms
Women psychiatric symptoms
rehabilitation
spa treatment

Semantics

Type Source Name
disease MESH Long COVID
disease MESH anxiety
disease MESH depression
disease MESH numbness
disease MESH memory loss
disease MESH sleep disorders
disease MESH neurological disorders
disease IDO history
disease MESH SARS CoV 2 infection
disease MESH ageusia
disease MESH altered taste
disease MESH inflammation
disease MESH thrombosis
disease MESH sequelae
drug DRUGBANK Oxygen
pathway REACTOME Immune System
disease IDO blood
disease MESH syndrome
disease MESH paresthesia
drug DRUGBANK Methylergometrine
disease MESH multiple sclerosis
disease MESH stroke
disease MESH Parkinson’s disease
disease MESH epilepsy
disease MESH cardiovascular diseases
disease MESH coronary artery disease
disease MESH heart failure
disease MESH myocardial infarction
disease MESH atrial fibrillation
disease MESH peripheral artery disease
disease MESH chronic obstructive pulmonary disease
disease MESH emphysema
disease MESH pneumoconiosis
disease MESH asthma
pathway KEGG Asthma
disease MESH rheumatic diseases
disease MESH rheumatoid arthritis
pathway KEGG Rheumatoid arthritis
disease MESH ankylosing spondylitis
disease MESH cancer
disease MESH blindness
disease MESH Lyme disease
disease IDO symptom
drug DRUGBANK Isoxaflutole
disease MESH lifestyle
disease IDO intervention
disease MESH hypertension
disease MESH diabetes mellitus
disease MESH Hypothyroidism
disease MESH Gout
disease MESH benign prostatic hyperplasia
drug DRUGBANK Water
drug DRUGBANK Pearl (hyriopsis cumingii)
drug DRUGBANK Hyaluronic acid
drug DRUGBANK Trestolone
pathway KEGG Circadian rhythm
disease MESH infection
disease MESH hypoxia
disease MESH cognitive dysfunction
drug DRUGBANK Hydrocortisone
disease MESH atrophy
drug DRUGBANK Coenzyme M
drug DRUGBANK Dinoprostone
disease MESH migraine
disease MESH Neurological manifestations
disease MESH Brain fog
disease MESH Chronic Fatigue Syndrome
drug DRUGBANK Sodium hydroxide
disease IDO role
disease MESH Fibromyalgia
disease IDO cell
disease MESH osteoarthritis
disease MESH back pain
disease MESH Psychiatric disorders
drug DRUGBANK Follitropin
drug DRUGBANK Testosterone
drug DRUGBANK Estradiol
disease MESH spastic
disease MESH Functional Status
disease MESH Dyspnea

Original Article

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