Publication date: Dec 01, 2025
Patients with severe coronavirus disease 2019 (COVID-19) have been reported to show hypoxia without displaying typical clinical signs or symptoms, called “happy hypoxia. ” To explore the potential of happy hypoxia as a distinctive symptom of COVID-19, we compared vital signs in the triage phase between patients with and without COVID-19. We retrospectively identified emergency patients with and without COVID-19 admitted to Rakuwakai Marutamachi Hospital, Kyoto, Japan, between January 2021 and December 2021. 317 patients were analyzed. Multivariate logistic regression analysis, including all vital signs, demonstrated that the respiratory rate was not statistically associated with COVID-19 (odds ratio, 0. 94, p = 0. 058), suggesting that happy hypoxia may not be a distinct hallmark of COVID-19.
| Concepts | Keywords |
|---|---|
| Coronavirus | COVID-19 |
| December | hypoxia |
| Happy | respiratory rate |
| Japan | triage |
| vital signs |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | hypoxia |
| disease | MESH | Coronavirus disease 2019 |
| disease | IDO | symptom |
| disease | MESH | emergency |
| disease | MESH | Long Covid |