Impact of Consensus Guidelines, Clinical Trials, and COVID-19 on Fractionation Practices for Node-negative Intact Breast Cancer.

Publication date: Feb 04, 2025

To evaluate whether hypofractionated radiotherapy (HF-RT) in node-negative intact breast cancer significantly increased after guideline updates, trial publications, and COVID-19. Patients with node-negative breast cancer undergoing lumpectomy and adjuvant RT were identified in the National Cancer Database. Receiving ≥25 and 20 fractions defined conventional RT (CF-RT). Patient characteristics were compared with X2 testing. Joinpoint analysis identified when fractionation significantly changed. Variables associated with HF-RT were identified by univariate and multivariate (MVA) logistic regression. Two-sided P-value

Concepts Keywords
Cancer Breast
Covid Cancer
Database Clinical
Radiotherapy Consensus
Covid
Fractionation
Guidelines
Hf
Identified
Intact
Negative
Node
Practices
Rt
Trials

Semantics

Type Source Name
disease MESH COVID-19
disease MESH Breast Cancer
pathway KEGG Breast cancer
disease MESH Cancer

Original Article

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