Investigation of renal function in patients with long COVID in the Amazon region: a cross-sectional study.

Publication date: Feb 11, 2025

COVID-19 became a pandemic disease in 2020, with multisystem involvement and high renal morbidity during the acute phase. Some affected patients began to present new or persistent symptoms in a condition known as Long COVID. The study aimed to evaluate renal function using clinical and laboratory findings, and to establish the frequency and staging of renal function decline in Long COVID patients, as well as the associated factors. This is a cross-sectional observational study that selected participants from a Long COVID clinical care program between 2020 and 2022. A total of 246 patients were selected for this study, and renal function decline was found in 83 (33. 7%). Patients over 60 years (29. 6%) and those who developed glycaemic alterations (41. 8%) exhibited a higher prevalence of renal outcomes in long COVID. Some laboratory test as LDH levels and glycated hemoglobin seems to have a statistic relation with a decrease in renal function (p

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Concepts	Keywords
Amazon	Acute kidney injury
Pandemic	Adult
Renal	Aged
	Aged, 80 and over
	Brazil
	COVID-19
	Cross-Sectional Studies
	Female
	Humans
	Kidney
	Kidney Function Tests
	Laboratory markers
	Long COVID
	Male
	Middle Aged
	Renal function
	SARS-CoV-2

Semantics

Type	Source	Name
disease	MESH	long COVID
disease	MESH	COVID-19
disease	MESH	morbidity
pathway	REACTOME	Reproduction
disease	MESH	Infectious Diseases
disease	MESH	infection
disease	MESH	acute respiratory distress syndrome
disease	MESH	death
disease	MESH	sequelae
drug	DRUGBANK	Aspartame
disease	MESH	Acute kidney injury
disease	MESH	abnormalities
disease	MESH	causes
disease	MESH	hypercoagulability
disease	MESH	shock
disease	MESH	hypovolemia
disease	MESH	rhabdomyolysis
disease	IDO	acute infection
disease	MESH	metabolic syndromes
disease	MESH	diabetes mellitus
disease	IDO	infected population
drug	DRUGBANK	Trestolone
drug	DRUGBANK	Ethionamide
disease	IDO	symptom
disease	MESH	chest pain
disease	MESH	cough headache
disease	MESH	brain fog
disease	MESH	chronic renal disease
disease	MESH	Respiratory Diseases
disease	MESH	Kidney Disease
drug	DRUGBANK	Creatinine
drug	DRUGBANK	Urea
disease	IDO	blood
drug	DRUGBANK	Sulodexide
drug	DRUGBANK	Coenzyme M
disease	IDO	reagent
drug	DRUGBANK	Dextrose unspecified form
disease	MESH	proteinuria
disease	MESH	hypertension
disease	MESH	overweight
disease	MESH	comorbidity
disease	MESH	cardiovascular disease
drug	DRUGBANK	Methionine
drug	DRUGBANK	Honey
disease	MESH	syndrome
drug	DRUGBANK	Cholesterol
disease	MESH	Prediabetes
disease	MESH	non communicable diseases
disease	MESH	hyperglycemia
disease	MESH	obesity
disease	MESH	edema
disease	MESH	inflammation
drug	DRUGBANK	Human Serum Albumin
drug	DRUGBANK	Indoleacetic acid
disease	MESH	viral load
disease	IDO	production
drug	DRUGBANK	Angiotensin II
disease	IDO	process
disease	MESH	privacy
disease	IDO	facility
drug	DRUGBANK	Guanosine
disease	MESH	critically ill
disease	MESH	Fanconi syndrome
drug	DRUGBANK	Imidacloprid
disease	MESH	diabetic nephropathy
drug	DRUGBANK	Carboxyamidotriazole

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