mRNA delivery with templated dynamic covalent polymers.

Publication date: Feb 17, 2025

Messenger RNA is a novel therapeutic modality which was key in curbing the Covid-19 pandemic. However, the delivery of mRNA in cells requires the development of smart vectors. We here report on amphiphilic dynamic covalent polymers formed in situ through RNA templating, and show effective nanoparticle formation and delivery of EGFP mRNA in cells.

Concepts Keywords
Covid Covalent
Mrna Covid
Nanoparticle Curbing
Pandemic Delivery
Therapeutic Dynamic
Key
Messenger
Modality
Mrna
Pandemic
Polymers
Requires
Smart
Templated
Therapeutic

Semantics

Type Source Name
disease MESH Covid-19 pandemic

Original Article

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