Nowcasting reported covid-19 hospitalizations using de-identified, aggregated medical insurance claims data.

Publication date: Feb 18, 2025

We propose, implement, and evaluate a method for nowcasting the daily number of new COVID-19 hospitalizations, at the level of individual US states, based on de-identified, aggregated medical insurance claims data. Our analysis proceeds under a hypothetical scenario in which, during the Delta wave, states only report data on the first day of each month, and on this day, report COVID-19 hospitalization counts for each day in the previous month. In this hypothetical scenario (just as in reality), medical insurance claims data continues to be available daily. At the beginning of each month, we train a regression model, using all data available thus far, to predict hospitalization counts from medical insurance claims. We then use this model to nowcast the (unseen) values of COVID-19 hospitalization counts from medical insurance claims, at each day in the following month. Our analysis uses properly-versioned data, which would have been available in real-time at the time predictions are produced (instead of using data that would have only been available in hindsight). In spite of the difficulties inherent to real-time estimation (e. g., latency and backfill) and the complex dynamics behind COVID-19 hospitalizations themselves, we find altogether that medical insurance claims can be an accurate predictor of hospitalization reports, with mean absolute errors typically around 0. 4 hospitalizations per 100,000 people, i. e., proportion of variance explained around 75%. Perhaps more importantly, we find that nowcasts made using medical insurance claims are able to qualitatively capture the dynamics (upswings and downswings) of hospitalization waves, which are key features that inform public health decision-making.

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Concepts Keywords
Accurate Aggregated
Hospitalizations Claims
Month Counts
Upswings Covid
Data
Day
Hospitalization
Hospitalizations
Hypothetical
Identified
Insurance
Month
Nowcasting
Real
Scenario

Semantics

Type Source Name
disease MESH covid-19
disease MESH Long Covid
pathway REACTOME Reproduction
drug DRUGBANK Coenzyme M
drug DRUGBANK Etoperidone
drug DRUGBANK Acetohydroxamic acid
disease MESH Emergency
disease IDO pathogen
disease MESH influenza
drug DRUGBANK Cysteamine
disease MESH uncertainty
drug DRUGBANK Alpha-1-proteinase inhibitor
drug DRUGBANK Methionine
drug DRUGBANK Isoxaflutole

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