Shengmai Liquid for Long COVID Fatigue: a Randomized Placebo-controlled Trial.

Publication date: May 18, 2025

The goal of this clinical trial is to learn if Shengmai liquid works to treat Long Covid fatigue. It will also learn about the safety of Shengmai liquid. The main questions it aims to answer are: * Dose the Shengmai liquid will reduce the level of fatigue in the participants and reduce the fatigue scale score of the participants? * Dose the Shengmai liquid will reduce the level of anxiety and depression in the participants and improve the sleep quality and quality of life of the participants Researchers will compare Shengmai oral liquid to a placebo (a look-alike substance that contains no drug) to see if Shengmai liquid works to treat Long Covid fatigue. Participants will: * Take Shengmai liquid or a placebo every day for 8 weeks. * Visit the clinic once every 4 weeks for check up and test. There are a total of two telephone follow-ups, one follow-up 15 days after the treatment starts and another follow-up 30 days after the treatment ends. * Participants’ medication responses and scale scores will be recorded.

Concepts Keywords
Aminotransferase Covid
Beijing Criteria
Breastfeeding Diseases
Epilepsy Fatigue
Weeks Liquid
Liver
Long
Participants
Placebo
Reduce
Screening
Serum
Shengmai
Treatment
Trial

Semantics

Type Source Name
disease MESH Long COVID
disease MESH anxiety
disease MESH depression
disease MESH sleep quality
disease IDO quality
disease MESH syndrome
drug DRUGBANK Oxygen
disease IDO history
disease MESH liver disease
disease MESH alcoholic fatty liver
disease MESH hepatitis B
pathway KEGG Hepatitis B
disease MESH infection
disease MESH primary biliary cirrhosis
disease MESH acute liver failure
drug DRUGBANK Creatinine
disease MESH congestive heart failure
disease MESH stroke
disease MESH myocardial infarction
disease MESH hypertension
disease IDO blood
disease MESH abnormalities
disease MESH atrioventricular block
disease MESH left bundle branch block
pathway KEGG Influenza A
disease MESH influenza
disease MESH infectious diseases
disease MESH epilepsy
disease MESH convulsions
disease MESH mental illness
disease MESH tumors
disease MESH chronic fatigue syndrome
disease MESH autoimmune diseases
disease MESH rheumatoid arthritis
pathway KEGG Rheumatoid arthritis
disease MESH systemic lupus erythematosus
pathway KEGG Systemic lupus erythematosus
disease MESH allergy

Original Article

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