Publication date: May 29, 2025

During the COVID-19 pandemic, accurate measurement of vaccination status was important for guiding prevention efforts. We assessed the accuracy of electronic health record (EHR) COVID-19 vaccination compared with survey self-reported vaccination status using data from a cross-sectional study among pregnant women and non-pregnant adults in the Vaccine Safety Datalink (VSD) between 2021 and 2022, where self-report was considered the reference standard. We measured sensitivity and specificity of EHR vaccine data compared with the self-reported measure and estimated vaccination rates from EHR data. EHR data were obtained initially in November 2021, updated in April 2022, and record review in July 2022. Vaccination coverage increased in pregnant/formerly pregnant women and non-pregnant adult respondents by 23. 9% and 9. 2%, respectively, over 9 months. Estimates of sensitivity based on initial EHR data were 66. 0% and 77. 3% for pregnant women and non-pregnant people overall and between 41% and 66% for pregnant, non-Hispanic Black, and Hispanic, Spanish-speaking respondents. With matured, chart reviewed EHR data from April 2022, the sensitivity and specificity of EHR vaccine status relative to self-report were >93%. EHR data was a reasonable source of COVID-19 vaccination status during the pandemic and showed high accuracy with self-reported data after allowing EHR data to mature.

Semantics

Original Article