Feasibility randomised controlled trial to assess the delivery of a novel isometric exercise intervention for people diagnosed with uncomplicated stage 1 hypertension in the National Health Service: key quantitative findings.

Publication date: Jun 04, 2025

The aim of this study was to determine the feasibility of delivering personalised isometric exercise (IE) for people with stage 1 hypertension. Is it feasible to deliver an isometric wall squat intervention in the National Health Service and what sample size is required to conduct an appropriately powered effectiveness randomised controlled trial (RCT)? Randomised controlled open-label multicentre feasibility study of IE compared with standard care in unmedicated people with stage 1 hypertension. Initially, the study aimed to recruit through primary care, but this process coincided with the advent of the COVID-19 pandemic. Therefore, we shifted focus to direct-to-public advertising and delivery in secondary care. People with unmedicated stage 1 hypertension aged over 18 able to perform IE were included. Patients were excluded if average home systolic blood pressure (sBP)

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Concepts Keywords
Advent Adult
Clinical Aged
Hypertension Clinical Trial
Randomised COVID-19
Stage Exercise
Exercise Therapy
Feasibility Studies
Female
Humans
Hypertension
Hypertension
Male
Middle Aged
SARS-CoV-2
State Medicine
United Kingdom

Semantics

Type Source Name
disease IDO intervention
disease MESH hypertension
disease IDO process
disease MESH COVID-19 pandemic
disease IDO blood

Original Article

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