Increased complications of proximal femur fractures during the COVID-19 pandemic: a nationwide medical claims database study in Japan.

Publication date: Jun 10, 2025

Coronavirus disease 2019 (COVID-19) is a worldwide pandemic, and mortality increases in elderly patients with comorbidities. This study aims to examine the in-hospital complications and mortality for elderly patients with proximal femur fractures during the COVID-19 pandemic or countermeasure periods. The proximal femur fractures undergoing surgery during the COVID-19 pandemic or countermeasure period were compared with the pre-pandemic in a Japanese national inpatient data. The assessed outcomes were the development of pneumonia, deep vein thrombosis (DVT), pulmonary embolism (PE), and mortality during hospitalization in two periods, and those for COVID-19-positive patients. A total of 284,922 proximal femur fractures aged over 65 years were included. In the COVID-19 pandemic period compared to the pre-pandemic, the odds of pneumonia, DVT, PE, and mortality decreased to 0. 942 (95% confidence interval [CI]: 0. 901 - 0. 986, P = 0. 0102) and 0. 839 (95% CI: 0. 745 - 0. 946, P = 0. 004), increased to 1. 153 (95% CI: 1. 112 - 1. 195, P 

Concepts Keywords
Coronavirus Complication
Elderly COVID-19
Increased Mortality
Japanese Nationwide cohort study
Surgery Proximal femur fracture

Semantics

Type Source Name
disease MESH complications
disease MESH COVID-19 pandemic
disease MESH pneumonia
disease MESH deep vein thrombosis
disease MESH pulmonary embolism
disease MESH Long Covid

Original Article

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