Publication date: Jun 15, 2025
Functional validation involved CRISPR-Cas9 gene editing and in vitro assays using primary nasal epithelial cells with targeted mutations. Gene expression in LC cases was compared to healthy controls (n=51). The results showed that at 36 and 1218 months post-COVID, transcriptomes were linked to inflammatory pathways (padj Hierarchical clustering was applied to define transcriptomic and cellular clusters, and gene expression patterns, gene set enrichment, and related pulmonary traits were an3ealyzed. Cell type proportions were inferred using deconvolution based on a single-cell dataset.
| Concepts | Keywords |
|---|---|
| Allergy | Com |
| An3ealyzed | Covid |
| June | Credit |
| Medicine | Epithelial |
| Researchers | Expression |
| Inflammatory | |
| Istock | |
| Linked | |
| Months | |
| Nasal | |
| Photo | |
| Precision | |
| Profiles | |
| Transcriptomes | |
| Transcriptomic |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | infection |
| disease | IDO | cell |
| disease | MESH | COVID-19 |
| drug | DRUGBANK | Oxygen |
| disease | MESH | Allergy |
| disease | MESH | long COVID |
| drug | DRUGBANK | Coenzyme M |
Original Article
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