Comparison of PEEP tables based on oxygenation vs. driving pressure-guided PEEP titration in patients with severe acute respiratory syndrome due to COVID-19.

Publication date: Jun 23, 2025

To evaluate the positive end-expiratory pressure (PEEP) values with decremental PEEP titration based on driving pressure (ΔP) were different in comparison with PEEP-FiO2 tables in patients with Severe Acute Respiratory Syndrome due to COVID-19 (CARDS). Retrospective cohort study at academic ICU in Brazil with adults with SARS due to COVID-19. The PEEP titration obtained by Best-ΔP was compared with values from PEEP-FiO2 tables. A total of 91 patients were included (141 titrations), with a median PaO2/FiO2 of 133 (97-170). The PEEP titration by ΔP was similar to the ARDSnet table (p = 0. 83) and different from the LOVs and ALVEOLI tables (p 30 kg/m2 was different (n = 73, p

Concepts Keywords
Academic COVID-19
Brazil Driving pressure
Covid Mechanical ventilation
Driving
P30kg

Semantics

Type Source Name
disease MESH severe acute respiratory syndrome
disease MESH COVID-19
disease MESH Acute respiratory distress syndrome

Original Article

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