Publication date: Jul 01, 2025
To understand how the population immunity evolved over time and possible susceptibility of the Sri Lankan population to emerging SARS-CoV-2 variants, we proceeded to evaluate the changes in antibody positivity rates to omicron variants BA. 2.75 and XBB. 1.5 and for selected sarbecoviruses. The haemagglutination test was carried out to determine the presence of antibodies against the RBD of the SARS-CoV-2 omicron variants XBB. 1.5 and BA. 2.75 and the RBD of the sarbecoviruses RaTG13, WIV1, Khosta-2, and SARS-CoV-1, in individuals aged 5-80 years of age in years 2020 (n = 381), 2022 (n = 432), and 2023 (n = 382). The highest positivity rates for BA. 2.75, RaTG13, WIV1, Khosta-2, and SARS-CoV-1 were seen in 2022, with positivity rates significantly declining for many of the viruses except XBB. 1.5 and Khosta-2 by 2023. The positivity rates for Khosta-2 (p

Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | susceptibility |
| disease | MESH | COVID-19 |