Publication date: Jun 20, 2025

A clinical survey on 909 patients with SARS-CoV-2 subvariant BF. 7 infection was conducted in Hohhot First Hospital in Hohhot, China, from October 3 to October 22, 2022. Medical records of patients were reviewed by 2 physicians, respectively. The majority of cases (over 80%) showed mild symptoms, while 25% had a history of chronic medical illness or comorbidities, including cardiovascular and cerebrovascular diseases (14%), metabolic disease (7%), obesity (4%) and others. Common symptoms of BF. 7 infection included cough (70%), sore throat (53%), expectoration (51%), and fever (41%). Around 75% of patients were discharged within 2 weeks of noninvasive mechanical ventilation and traditional Chinese medicine treatment. This study also resulted in that vaccination was ineffective against BF. 7 virus infection, while elderly patients with incomplete COVID-19 vaccination and preexisting chronic diseases were at higher risk for moderate or severe BF. 7 infection. In conclusion, this study analyzed clinical characteristics of patients infected by BF. 7 virus, emphasizing the imperative to further explore effective vaccine and develop novel prevention and treatment strategies to cope with such a continuously mutating and evolving RNA virus infection and to minimize its threat and impact on human health, especially for vulnerable population.

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