Publication date: Jul 01, 2025
Severe acute respiratory syndrome coronavirus 2 can cause acute respiratory distress syndrome, requiring prolonged invasive mechanical ventilation. However, patients with coronavirus disease 2019 (COVID-19) undergoing invasive mechanical ventilation experience barotrauma. We assessed whether limiting the maximum positive end-expiratory pressure (PEEP) may prevent barotrauma more effectively than using PEEP/fraction of inspired oxygen (FiO) in patients with COVID-19 undergoing invasive mechanical ventilation. We retrospectively included patients who met the diagnostic criteria at our center; they were divided into an ordinary PEEP group (PEEP/higher FiO table) and a limited PEEP group (maximum PEEP of
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | critically ill |
| disease | MESH | COVID-19 |
| disease | MESH | acute respiratory distress syndrome |
| drug | DRUGBANK | Oxygen |
| drug | DRUGBANK | Methionine |
Original Article
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