Population-Based Analysis of Vaccination Status and Post-Vaccination Adverse Events in Adults Aged 55 and Older.

Publication date: Jun 17, 2025

Background/Objectives: Older adults face increased vulnerability to infectious diseases such as influenza, pneumococcal infections, and COVID-19. Vaccination remains a key public health strategy, yet coverage and adverse event data in this group are limited. This study aimed to assess the prevalence of vaccination and the occurrence of post-vaccination adverse events among individuals aged 55 and older in Płock, Poland, with particular attention to gender and age differences. Methods: A population-based cross-sectional study was conducted between January and November 2022 among 2040 adults aged ≥ 55 years. Participants completed a structured questionnaire on vaccination history (past 3 years) and adverse events following immunization (AEFI). Cognitive eligibility was assessed using the MMSE (≥27). Statistical analyses included t-tests, chi-square tests, and Pearson correlation coefficients with a significance level of p < 0. 05. Results: COVID-19 vaccination was reported by 86. 9% of participants, influenza vaccination by 45. 5%, and pneumococcal vaccination by 15. 1%. Women reported significantly more adverse events following COVID-19 vaccination compared to men (16. 1% vs. 8. 8%, p < 0. 001). A weak negative correlation was observed between age and number of vaccinations received (r = -0. 088, p = 0. 001), while age was positively correlated with adverse events following COVID-19 vaccination (r = 0. 175, p < 0. 001). Influenza vaccination was more common among men than women (50. 7% vs. 43. 4%, p < 0. 05). Conclusions: Vaccination coverage among older adults in Płock was highest for COVID-19 but remained suboptimal for influenza and pneumococcal vaccines. Women reported adverse events more frequently than men. These findings highlight the need for targeted vaccination strategies and gender-sensitive communication approaches.

Open Access PDF

Concepts Keywords
Immunization gender differences
Influenza older adults
Men vaccination coverage
November
Poland

Semantics

Type Source Name
disease MESH infectious diseases
disease MESH influenza
disease MESH pneumococcal infections
disease MESH COVID-19
disease IDO history
disease MESH chronic conditions
disease MESH morbidity
disease MESH infections
disease MESH pneumonia
disease MESH meningitis
disease MESH bacteremia
disease MESH respiratory infections
disease IDO process
disease MESH cognitive impairments
drug DRUGBANK Methionine
disease MESH hepatitis
disease MESH tetanus
disease MESH tick borne encephalitis
disease MESH joint pain
disease MESH measles
pathway KEGG Measles
disease MESH meningococcal infections
disease MESH jaundice
disease IDO site
disease IDO symptom

Original Article

(Visited 2 times, 1 visits today)