Publication date: Jun 30, 2025
We sought to assess the burden of disease of RSV and influenza in hospitalized children in the context of the COVID-19 pandemic and its preventive measures in the winter seasons from 2019/2020 to 2023/2024. We compared both diseases by means of a retrospective, single-center study from October 1, 2019, to April 30, 2024, including infants and children up to 18 years hospitalized due to an RSV and/or influenza infection at Clinic Donaustadt, Vienna. Infection had to be proven by polymerase chain reaction or antigen test. By evaluating each single hospital course, we analysed seasonality, detailed patient characteristics and parameters of disease severity. Overall, there were 894 children hospitalized, 561 due to RSV and 314 due to influenza, 19 due to both viruses. Cases with RSV infection were younger of age (mean: 16. 5 vs. 58. 1 months; p

Semantics
| Type | Source | Name |
|---|---|---|
| pathway | REACTOME | Influenza Infection |
| disease | MESH | COVID-19 pandemic |
| disease | MESH | influenza |
| disease | MESH | Infection |
| disease | MESH | RSV infection |
| disease | MESH | Morbidity |