Deciphering the YY1/ lncRNA BLACAT1/miR-605-3p axis in glioblastoma: implications for therapy.

Publication date: Jul 01, 2025

Glioblastoma multiforme (GBM), an aggressive brain cancer, requires novel therapeutic targets. This study investigates the YY1/lncRNA BLACAT1/miR-605-3p regulatory network in GBM pathogenesis. Using bioinformatics tools and TCGA-GBM datasets, we identified six miR-605-3p target genes (ARPC1B, FOSL1, H6PD, ITGA3, LMAN1, and PXN) strongly correlated with YY1 (p 

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Concepts Keywords
Cancer Aggressive
Glioblastoma Axis
H6pd Blacat1
Pathogenesis Brain
Therapy Cancer
Deciphering
Gbm
Glioblastoma
Implications
Lncrna
Mir
Multiforme
Requires
Therapy
Yy1

Original Article

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