The impact of remdesivir on renal and liver functions in severe COVID-19 patients with presence of viral load.

Publication date: Jul 01, 2025

The impact of remdesivir on renal and liver functions remains a matter of concern in advanced COVID-19 patients with high illness severity and presence of viral load. The laboratory results of the 114 patients (males 55. 8%, age 71 (59; 77) years) with a detectable viral load treated with remdesivir were compared with the controls. Baseline plasmatic creatinine (PCr)  0. 9). Changes of PCr were independent of the remdesivir therapy, the statistically significant confounders were baseline PCr levels (p 

Open Access PDF

Concepts Keywords
Males Adenosine Monophosphate
Pcr Adenosine Monophosphate
Renal Aged
Therapy Alanine
Viral Alanine
Antiviral Agents
Antiviral Agents
COVID-19
COVID-19 Drug Treatment
Creatinine
Creatinine
Female
Humans
Intensive care
Kidney
Liver
Liver Function Tests
Liver function tests
Male
Middle Aged
remdesivir
Remdesivir
Renal function
SARS-CoV-2
SARS-CoV-2
Urea
Urea
Viral Load
Viral load

Semantics

Type Source Name
disease MESH COVID-19
disease MESH viral load
drug DRUGBANK Creatinine
drug DRUGBANK Adenosine phosphate
drug DRUGBANK L-Alanine
drug DRUGBANK Urea

Original Article

(Visited 3 times, 1 visits today)