The COVIDTrach prospective cohort study on outcomes in 1982 tracheostomised COVID-19 patients during the first and second UK pandemic waves.

Publication date: Jul 02, 2025

COVIDTrach is a UK-wide, prospective cohort study evaluating tracheostomised COVID-19 patient outcomes and operator disease transmission. Early in the pandemic controversy surrounded optimal timing of tracheostomy insertion, however meta-analyses have since addressed this uncertainty. We report on our cohort’s data and outcomes to help inform the management of this disease and compare our findings to the literature. Our inclusion criteria were COVID-19 patients aged ≥ 18 undergoing tracheostomy following invasive ventilation. We recorded relevant characteristics, clinical parameters, intra-operative details and outcome data. Predictors for mortality and time to ventilatory wean were determined. Among 1982 patients, there was a 21% post-tracheostomy mortality and median intubation to tracheostomy time of 15 days (IQR 11-21). The median time to successful ventilatory wean post-tracheostomy was 12 days (IQR 7-20). Advancing age, greater FiO2 and PEEP requirements and inotrope or anticoagulant use were associated with increased mortality (p 

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Concepts Keywords
12days Adult
Covid Aged
Iqr Aged, 80 and over
Tracheostomy Cohort studies
COVID-19
COVID-19
Female
Humans
Intubation
Male
Middle Aged
Noninvasive ventilation
Pandemic
Pandemics
Prospective Studies
Prospective studies
Respiration, Artificial
SARS-CoV-2
Tracheostomy
Tracheostomy
Treatment Outcome
United Kingdom
Ventilator Weaning
Ventilator weaning

Semantics

Type Source Name
disease MESH COVID-19
disease MESH uncertainty
disease MESH Weaning

Original Article

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