Bayesian changepoint detection for epidemic models.

Publication date: Jul 01, 2025

This paper demonstrates how Bayesian stochastic filtering techniques can be used to detect changepoints in the transmission rate, as well as identify the rate itself, in the spread of disease using the susceptible-infectious-recovered (SIR) model. To better model real-world scenarios, a stochastic SIR model is considered where the transmission rate is unknown a priori, the number of people moving between compartments is perturbed by additional randomness, and the rate changes at unknown points in time. Changepoints can be used to model disruptions in disease spread, such as those caused by public health measures or new variants. We consider this problem in a Bayesian setting, where the unknown rate and changepoints are modelled as random variables with known prior distributions. This rate can be observed indirectly via the drift of a Brownian motion, before optimally filtering the transmission rate along with any changepoints using Bayesian stochastic filtering techniques. The methods are illustrated with an example using a real dataset from the COVID-19 pandemic, effectively detecting changepoints related to public health measures and the spread of the Omicron variant in the United Kingdom.

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Concepts Keywords
Bayesian Bayes Theorem
Changepoint COVID-19
Covid Epidemics
Models Epidemiological Models
Pandemic Humans
Pandemics
SARS-CoV-2
Stochastic Processes
United Kingdom

Semantics

Type Source Name
drug DRUGBANK Tropicamide
disease MESH COVID-19 pandemic
disease MESH infectious diseases
disease MESH infection
disease IDO process
drug DRUGBANK Coenzyme M
pathway REACTOME Reproduction
disease MESH death
drug DRUGBANK Dihydrostreptomycin
drug DRUGBANK Aspartame
drug DRUGBANK L-Arginine
drug DRUGBANK Serine
disease MESH measles
pathway KEGG Measles
disease MESH AIDS
drug DRUGBANK Carboxyamidotriazole
disease IDO symptom

Original Article

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