Publication date: Jul 05, 2025
This work presents a comprehensive investigation of symmetric (HJ-DD-UTFET) and asymmetric Source Drain Heterojunction Dual Dielectric Uniform Tunnel Field-Effect Transistors (A-SD-HJ-DD-UTFET) to achieve enhanced analog/RF, and linearity performance. The A-SD-HJ-DD-UTFET showcases an extremely low OFF current level of 8. 124 cD7 10 A/μm which surpasses the symmetric HJ-DD-UTFET by 5,470 times and presents a high ON-OFF ratio of 2. 83 cD7 10 representing a 6,261 times improvement. This enhanced performance occurs because of structural asymmetry which makes it suitable for high-end RF and biosensing purposes while reaching a peak transconductance of 536 uS. For dengue NS1 protein detection (_705 = 78. 7), the TCAD-driven model of the proposed A-SD-HJ-DD-UTFET biosensor delivers a distinctive label-free detection method, achieving a peak transconductance (g) of 577 uS, cut-off frequency (f) of 193 GHz, Gain-Bandwidth Product (GBP) of 201 GHz, Transconductance Generation factor (TGF) of 155 V, and gain transconductance frequency product (GTFP) of 25. 9 THz. These correspond to improvements of 51. 4%, 13. 5%, 26. 4%, 96. 4%, and 45. 5%, respectively, over SARS-CoV spike protein detection (_705 = 2). The A-SD-HJ-DD-UTFET biosensor also exhibits superior linearity performance during dengue NS1 protein detection through its desirable intercept points, minimal intermodulation distortion, and a well-maintained 1 dB compression point, affirming its potential as a high-speed, label-free RF biosensor for infectious disease Point of Care Testing (POCT) diagnostics.
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | dengue |
| disease | IDO | protein |
| disease | MESH | infectious disease |
| pathway | REACTOME | Infectious disease |
| drug | DRUGBANK | Albendazole |
| disease | IDO | process |
| drug | DRUGBANK | Coenzyme M |
| drug | DRUGBANK | Silicon |
| disease | MESH | infection |
| drug | DRUGBANK | Aspartame |
| disease | MESH | aids |
| disease | MESH | defects |
| drug | DRUGBANK | Flurbiprofen |
| pathway | REACTOME | Signal amplification |
| drug | DRUGBANK | Succimer |
| disease | IDO | quality |
| disease | IDO | blood |
| disease | MESH | influenza |
| drug | DRUGBANK | Dextrose unspecified form |
| drug | DRUGBANK | Heparin |
| disease | MESH | melanoma |
| pathway | KEGG | Melanoma |
| drug | DRUGBANK | Gelatin |
| drug | DRUGBANK | Indium |
| disease | IDO | intervention |
| disease | IDO | assay |
| drug | DRUGBANK | Dimercaprol |
| drug | DRUGBANK | Tricyclazole |
| drug | DRUGBANK | Nonoxynol-9 |
| disease | MESH | dengue hemorrhagic fever |
| disease | MESH | viral infection |
| disease | IDO | nucleic acid |
| drug | DRUGBANK | Mexiletine |
| drug | DRUGBANK | Gold |
| pathway | REACTOME | Reproduction |