Publication date: Dec 01, 2025

This study aims to investigate the influence of the COVID-19 lockdown period on anxiety, anger, loneliness and depression, four categories of negative emotions, in patients undergoing maintenance hemodialysis. A cross-sectional survey was conducted, and a total of 174 patients receiving maintenance hemodialysis at the Second Affiliated Hospital and Fourth Affiliated Hospital Hemodialysis Center of Anhui Medical University between October 20 and October 27, 2022, were selected as the study subjects. We used the Medical Staff Stress and Negative Emotions Scale (MSSNS) to assess the emotional changes in anxiety, anger, loneliness and depression in these patients before and during the lockdown. A total of 174 questionnaires were collected, all of which were valid. During the lockdown period, the scores for anxiety (18. 89 +/- 6. 83), anger (10. 20 +/- 3. 32), loneliness (10. 86 +/- 3. 81) and depression (14. 13 +/- 4. 24) were significantly higher than the scores before the lockdown for anxiety (16. 63 +/- 4. 64), anger (9. 74 +/- 2. 60), loneliness (10. 26 +/- 3. 35) and depression (13. 11 +/- 4. 24). These differences were statistically significant (p 

Semantics

Original Article