Oscillation in the SIRS model.

Publication date: Aug 21, 2025

We study the SIRS epidemic model, both analytically and on a square lattice. The analytic model has two stable solutions, post outbreak/epidemic (no infected, I=0) and the endemic state (constant number of infected: I>0). When the model is implemented with noise, or on a lattice, a third state is possible, featuring regular oscillations. This is understood as a cycle of boom and bust, where an epidemic sweeps through, and dies out leaving a small number of isolated infecteds. As immunity wanes, herd immunity is lost throughout the population and the epidemic repeats. The key result is that the oscillation is an intrinsic feature of the system itself, not driven by external factors such as seasonality or behavioural changes. The model shows that non-seasonal oscillations, such as those observed for the omicron COVID variant, need no additional explanation such as the appearance of more infectious variants at regular intervals or coupling to behaviour. We infer that the loss of immunity to the SARS-CoV-2 virus occurs on a timescale of about ten weeks.

Concepts Keywords
Covid COVID-19
Epidemic Endemic
Herd Epidemic model
Stable Epidemics
Weeks Epidemiological Models
Humans
Models, Biological
Omicron variant SARS-cov2
Oscillations
SARS-CoV-2
SIRS

Semantics

Type Source Name
drug DRUGBANK Pentaerythritol tetranitrate
disease MESH COVID-19

Original Article

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