The effect of COVID-19 vaccination on menstrual cycles of adolescents and young adults: a systematic review and meta-analysis.

Publication date: Jul 03, 2025

The binding of the SARS-CoV-2 spike protein from vaccination can affect the menstrual cycle. Most studies have focused on women of reproductive age, with less attention given to adolescent and young women, despite their increased risk of heightened responses to vaccines. Thus, we consolidated evidence on menstrual changes after COVID-19 vaccination for adolescent and young women. OVID MEDLINE, EMBASE and CINAHL databases were searched (January 2020-December 2024) for peer-reviewed studies on COVID-19 vaccination on menstruating people

Concepts Keywords
Covid COVID-19 vaccination
Menstrual menstruation
Vaccination reproductive health
Women

Semantics

Type Source Name
disease MESH COVID-19

Original Article

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