Reinfection Incidences in Health Care Workers and Non-Health Care Workers: A Single-Center Study in a Turkish SARS-CoV-2 Patient Cohort.

Publication date: Jul 07, 2025

The COVID-19 pandemic, which has killed millions of people worldwide, continues to be marked by waves of reinfections. We aimed to assess the incidence and clinical characteristics of reinfection in COVID- 19 cohort. A single-center descriptive study was conducted. Data were collected from all patients who tested positive for SARS-CoV-2 via PCR from March 18, 2020, the onset of the first major COVID-19 wave, until the end of 2020. All PCR-positive patients were followed-up, and those who had SARS-CoV-2 PCR positivity again at least 90 days after the initial onset were contacted via telemedicine. 5814 patients diagnosed with COVID-19 with PCR positive in the first wave were included. The incidence of reinfection among the cohort of patients infected with SARS-CoV-2 during the initial wave of COVID-19 was 0. 73%. Among healthcare workers, the 1-year reinfection rate was 2. 14%, 3. 9 times higher than non-healthcare workers. We observed that the clinical course was milder and less complicated in patients who had reinfection. In cases of reinfection among fully vaccinated individuals, statistically significantly fewer symptoms were observed. We observed that healthcare workers are at approximately four times greater risk of reinfection. Reinfections generally presented with a milder clinical course.

Concepts Keywords
Healthcare Adult
Killed Aged
Turkish Cohort Studies
COVID-19
COVID-19
Female
Health Personnel
healthcare workers
Humans
Incidence
Male
Middle Aged
Reinfection
reinfection
SARS-CoV-2
SARS-CoV-2
Turkey
vaccination

Semantics

Type Source Name
disease MESH Reinfection
disease MESH COVID-19 pandemic
disease MESH clinical course
disease MESH Long Covid

Original Article

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