Publication date: Jul 07, 2025
The COVID-19 pandemic posed a worldwide challenge for blood services. We aimed to evaluate the impact of the COVID-19 pandemic on blood donations and blood discards resulting from screening tests for transfused-transmitted infections (TTIs) in a Brazilian metropolitan. Time-series cohort study including data of all blood donors from January 2018 to December 2021 at the BrascEDlia Blood Center Foundation, Federal District, Brazil. The causal impact analysis was used to evaluate the impact of COVID-19 on blood donations, and a propensity score matching was used to evaluate the effect of the COVID-19 pandemic on the seroprevalence of TTIs. There were 205 965 blood donations during the study period. The blood donations significantly reduced soon after the onset of the COVID-19 pandemic in Brasilia, Brazil, in March 2020 until August 2020 (absolute effect per week: -2952; 95% CI: -4627 to -1355). However, from September 2020 to December 2021, blood donations had returned to the levels foreseen by the time-series model. Compared to the pre-COVID-19 period, the period between September 2020 and December 2021 was associated with a decrease of at least one reactive or indeterminate screening test for TTI (OR: 0. 753, 95% CI: 0. 665-0. 854, p
| Concepts | Keywords |
|---|---|
| August | blood donation |
| Brazil | blood safety |
| December | blood transfusion |
| Donations | blood‐borne infections |
| Pandemic | blood‐borne pathogens |
| COVID‐19 | |
| motivation |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 pandemic |
| disease | IDO | blood |
| disease | MESH | transfusion-transmitted infections |
| disease | MESH | infections |
| disease | MESH | Long Covid |